Science for a Healthier Tomorrow
Does a Longevity Diet Work in Humans?
In old mice a low-protein diet with added methionine cut fat and frailty without cutting calories but did not extend life; a human diabetes link was unadjusted.
Nutritious News
Science for a Healthier Tomorrow
Nutritious News
Science for a Healthier Tomorrow
Research Analysis
AllAppetite & SatietyDiet Claims & ControversiesExercise & Body CompositionFood Environment & BehaviorGLP-1 & MedicationsMetabolic HealthNutrition ResearchWeight Regulation
Does Processing Change How Food Is Metabolized?
A small crossover matched two meals on calories and nutrients. Insulin, energy use and fuel choice still differed — an acute lab signal, not weight or disease.
Does Creatine Build Muscle Without Exercise?
A 12-week trial found creatine raised lean mass by about 1.1 kg (2.4 lb) without exercise — but the estimate was imprecise and exercise status self-selected.
How Much Weight Loss Does Retatrutide Produce?
Two Phase 3 trials found the investigational drug retatrutide produced about 25% average weight loss in obesity without diabetes and 19% with type 2 diabetes.
Is Tirzepatide Better Than Semaglutide for Weight Loss?
A meta-analysis of 10 head-to-head studies found tirzepatide produced about 4 percentage points more weight loss than semaglutide, with more serious adverse events.
Does Time-Restricted Eating Work in PCOS?
A 6-month trial found a 6-hour eating window without calorie counting produced weight loss comparable to a 25% calorie cut in 76 women with PCOS — not a proven equal.
Is “Healthy” Ultra-Processed Food as Good?
In 55 UK adults, ultra-processed and minimally processed Eatwell diets both cut weight; the minimally processed one cut about 1 kg more. Critics dispute why.
How to keep weight off after GLP-1 ends?
Two Nature Medicine trials tested keeping weight off: an oral GLP-1 switch after injectables, and a probiotic after dieting. Neither tested stopping treatment.
Ultra-Processed Food and Weight Gain: What Happened When Calories Were Matched?
A crossover trial matched calories and macronutrients between ultra-processed and unprocessed diets in 43 young men. Fat mass rose about 1 kg on the ultra-processed diet; testosterone and sperm changes were non-significant trends. Two published critiques contest the interpretation.
Does ultra-processed food impact heart health risk? 51 study meta analysis.
A meta-analysis of 51 cohorts links each extra 100 g/day of ultra-processed food to about 14% higher cardiovascular-event risk. What the low certainty rating and the missed hypertension null mean.