Science for a Healthier Tomorrow
Does Creatine Build Muscle Without Exercise?
A 12-week trial found creatine raised lean mass by about 1.1 kg (2.4 lb) without exercise — but the estimate was imprecise and exercise status self-selected.
Do Diet Drinks Work as Well as Water for Weight Loss?
A 2-year randomized trial found adults in a weight program who drank non-nutritive-sweetened soft drinks were not worse off than water drinkers.
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How Much Weight Loss Does Retatrutide Produce?
Two Phase 3 trials found the investigational drug retatrutide produced about 25% average weight loss in obesity without diabetes and 19% with type 2 diabetes.
Is Tirzepatide Better Than Semaglutide for Weight Loss?
A meta-analysis of 10 head-to-head studies found tirzepatide produced about 4 percentage points more weight loss than semaglutide, with more serious adverse events.
Does Time-Restricted Eating Work in PCOS?
A 6-month trial found a 6-hour eating window without calorie counting produced weight loss comparable to a 25% calorie cut in 76 women with PCOS — not a proven equal.
Does Eating the Same Meals Help You Lose Weight?
In a 12-week program, adults whose food logs showed more repeated foods and steadier calories lost somewhat more weight — 5.9% vs 4.3%, an association, not proof of cause.
Does Weight Loss Rewire the Gut-Brain Loop?
Preliminary: in an uncontrolled study of 25 adults who lost weight, gut-bacteria and brain-activity shifts tracked together — an association, not proof that weight loss rewires the brain.
Can Ultra-Processed Food Hurt Your Focus?
Preliminary: more ultra-processed food tracked with slightly lower attention scores and a higher dementia-risk score — a small association, not proof of cause, and no memory link.
Does WHO Recommend Weight Loss Drugs?
The WHO’s first global GLP-1 obesity guideline makes two conditional recommendations on moderate-to-low certainty evidence. Who it covers, and who it does not.
Is “Healthy” Ultra-Processed Food as Good?
In 55 UK adults, ultra-processed and minimally processed Eatwell diets both cut weight; the minimally processed one cut about 1 kg more. Critics dispute why.
Do Weight Loss Drugs Lower Cancer Risk?
A large observational study found a 41% lower relative risk of obesity-associated cancer diagnoses in adults on GLP-1 drugs. Its design cannot show cause.