Science for a Healthier Tomorrow
Science for a Healthier Tomorrow
Science for a Healthier Tomorrow
Preliminary: more ultra-processed food tracked with slightly lower attention scores and a higher dementia-risk score — a small association, not proof of cause, and no memory link.
The WHO's first global GLP-1 obesity guideline makes two conditional recommendations on moderate-to-low certainty evidence. Who it covers, and who it does not.
In 55 UK adults, ultra-processed and minimally processed Eatwell diets both cut weight; the minimally processed one cut about 1 kg more. Critics dispute why.
A large observational study found a 41% lower relative risk of obesity-associated cancer diagnoses in adults on GLP-1 drugs. Its design cannot show cause.
Preliminary: a supervised ketogenic diet was tolerable in 22 adults with anorexia nervosa — a single-arm trial that cannot show it worked.
In a two-week crossover trial, 31 women ate inside an 8-hour window. Insulin sensitivity and cardiometabolic markers did not improve — an imprecise null.
A small trial in adults 65+ cut ultra-processed food to about 13% of calories: they ate less, lost about 4 kg, and markers improved — but the cause is unclear.
A 14-trial meta-analysis found higher step counts tracked with more weight kept off — but 8,500 steps was the average walked, not a proven target.
Two Nature Medicine trials tested keeping weight off: an oral GLP-1 switch after injectables, and a probiotic after dieting. Neither tested stopping treatment.
In the first controlled-feeding trial in adults 18-25, the full sample showed no difference in test-meal intake after two weeks of ultra-processed food. Only the 18-21 group ate more — an exploratory result from 11 people at a single meal.